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Digital slide: |
Case 4-1: Mesenteric lymph node, H&E, Treated: cyclophosphamide 3 mg/kg Case 4-2: Peyer's patches, H&E, Treated: cyclophosphamide 3 mg/kg Case 4-3: Spleen, B lymphocytes, Control Case 4-4: Spleen, T lymphocytes, Control Case 4-5: Spleen, B lymphocytes, Treated: cyclophosphamide 6 mg/kg Case 4-6: Spleen, T lymphocytes, Treated: cyclophosphamide 6 mg/kg Case 4-7: Mesenteric lymph node, B lymphocytes, Treated: cyclophosphamide 6 mg/kg Case 4-8: Peyer's patches, B lymphocytes, Treated: cyclophosphamide 6 mg/kg |
Species / breed: |
Rat |
Sex: |
Male and female |
Age: |
10 weeks |
Study type: |
2-week repeated dose |
Treatment: |
Cyclophosphamide |
Clinical findings: |
None |
Organ(s): |
Bone marrow, mesenteric lymph nodes, Peyer's patches, spleen |
Gross finding(s): |
Small spleen in high dosed group (6mg/kg) |
Staining: |
H&E, B- and T-lymphocytes |
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