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Digital slide(s): |
Case 8a Case 8b Case 8c |
Species / breed: |
Brown Norway rat |
Sex: |
Female |
Age: |
10 weeks (at start of dosing). |
Study type: |
0, 7, 10, 14 and 21-day oral (gavage) |
Treatment: |
Nevirapine 150mg/kg/day |
Clinical findings: |
Pruritus, swollen and red ears, skin ulceration (back) |
Organ(s): |
Skin |
Gross finding(s): |
Correlate to clinical observation |
Staining: |
H&E |
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